Methyl‐CpG‐binding protein 2 is phosphorylated by homeodomain‐interacting protein kinase 2 and contributes to apoptosis
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Pea DNA topoisomerase I is phosphorylated and stimulated by casein kinase 2 and protein kinase C.
DNA topoisomerase I catalyzes the relaxation of superhelical DNA tension and is vital for DNA metabolism; therefore, it is essential for growth and development of plants. Here, we have studied the phosphorylation-dependent regulation of topoisomerase I from pea (Pisum sativum). The purified enzyme did not show autophosphorylation but was phosphorylated in an Mg(2+)-dependent manner by endogenou...
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A method is presented for the rapid purification of dog thyroid calcyphosine, a protein previously identified as a major substrate for cyclic AMP-dependent protein kinase in dog thyroid slices stimulated by thyrotropin [Lecocq, Lamy and Dumont (1979) Eur. J. Biochem. 102, 147-152]. The protein was previously identified as a spot on two-dimensional gels and is now purified in its native form by ...
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Bromodomain factor 1 (Bdf1) associates with Saccharomyces cerevisiae TFIID and corresponds to the C-terminal half of higher eukaryotic TAF1. It also associates with the SWR-C complex, which is important for Htz1 deposition. Bdf1 binds preferentially to acetylated histone H4. Bdf1 is phosphorylated, but the mechanism and significance of this modification have been unclear. Two distinct regions w...
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Serum deprivation of Ha-ras-transformed brown adipocyte cell line resulted in a dramatic apoptotic cell death, as detected either by DNA laddering or by an increase in the percentage of hypodiploid cells or by nuclei condensation and fragmentation, as compared with immortalized cell line or primary fetal brown adipocytes. Moreover, transient transfection of immortalized brown adipocytes with a ...
متن کاملFull length cardiac Na + - Ca 2 + exchanger ( NCX 1 ) protein is not 1 phosphorylated by protein kinase A ( PKA ) 2 3
1 Full length cardiac Na-Ca exchanger (NCX1) protein is not 1 phosphorylated by protein kinase A (PKA) 2 3 Pimthanya Wanichawan1,2, William E. Louch1,2, Kristin H. Hortemo1,2, Bjørg 4 Austbø1,2, Per Kristian Lunde1,2, John D. Scott3, Ole M. Sejersted1,2 and 5 Cathrine R. Carlson . 6 7 Institute for Experimental Medical Research, Oslo University HospitalUllevaal, 8 Oslo, Norway, Center for Heart...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2009
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2009.217